| Week |
# |
Date |
Topic (click for links, outlines, etc.) |
Reading |
|
| 1 |
1 |
Mar 28 |
Course intro; overview of virology and immunology |
Ch. V2, I1, p. V11-19, I1-8 |
| 2 |
Mar 30 |
Innate immunity - barriers, phagocytosis |
Ch. I1-2, p. 3-4, 14, 21-30 |
| 3 |
Apr 1 |
Innate immunity - NK cells, complement |
Ch. I2, p. 30-38 |
|
| 2 |
4 |
Apr 4 |
Antigen presentation and MHC |
Ch. I1, I3, p. 8-14, 41-53 |
| 5 |
Apr 6 |
Antigen processing |
Ch. I3, p. 53-60 |
| 6 |
Apr 8 |
Antibody structure and diversity |
Ch. I4, p. 63-70, 75-76 |
|
| 3 |
7 |
Apr 11 |
T cell diversity; selection and maturation of lymphocytes |
Ch. I1, I4, p. 14-19, 64-66, 70-74, 76-82 |
| 8 |
Apr 13 |
CMI: Activation of T cells |
Ch. I1, I5, p. 8-14, 83-94 |
| 9 |
Apr 15 |
CMI: Differentiation of T cells, signal transduction |
Ch. I5, p. 94-103 |
|
| 4 |
10 |
Apr 18 |
CMI: Elimination of infection |
Ch. I6, p. 105-120 |
| 11 |
Apr 20 |
Humoral immunity: Activation of B cells |
Ch. I1, I7, p. 8-14, 123-132 |
| 12 |
Apr 22 |
Humoral immunity: Antibody production |
Ch. I7, p. 133-141 |
|
| 5 |
13 |
Apr 25 |
Humoral immunity: Elimination of infection |
Ch. I8, p. 143-157 |
| 14 |
Apr 27 |
Tolerance |
Ch. I9, p. 161-172 |
| 15 |
Apr 29 |
Viral replication and pathogenesis |
Ch. V1-2, p. 3-19 |
|
| 6 |
16 |
May 2 |
DNA viruses: SV40 |
Ch. V17, p. 286-296 |
| 17 |
May 4 |
DNA viruses: Herpes virus |
Ch. V18, p. 311-332 |
| 18 |
May 6 |
(+)RNA viruses: Polio virus and SARS virus |
Ch. V15, p. 231-241, 248-251 |
|
| 7 |
19 |
May 9 |
(–) RNA viruses: Influenza virus |
Ch. V16, p. 258, 267-272 |
| 20 |
May 11 |
dsRNA viruses: Reovirus |
Ch. V16, p. 276-279 |
| 21 |
May 13 |
Retroviruses: HIV |
Ch. V20, p. 356-372 |
|
| 8 |
22 |
May 16 |
How pathogens evade immune defenses |
Ch. I2, I6, I8, V7, p. I36, I118-120, I157-158, V88-90 |
| 23 |
May 18 |
Vaccination |
Ch. I8, V8, p. I158-159, V96-102 |
| 24 |
May 20 |
Building better vaccines |
TBA |
|
| 9 |
25 |
May 23 |
Antiviral drugs |
Ch. V8, p. 106-110 |
| 26 |
May 25 |
Autoimmunity |
Ch. I9, V7, p. I162-163, I172-176, V86-88 |
| 27 |
May 27 |
Hypersensitivity: Allergies, etc. |
Ch. I11, p. 193-207 |
|
| 10 |
|
May 30 |
Memorial Day |
|
| 28 |
Jun 1 |
Transplant immunology |
Ch. I10, p. 184-192 |
| 29 |
Jun 3 |
Cancer |
Ch. V17, V20, I10, p. V296-299, V370-371, I177-184 |
|
| |
|
Jun 8 |
Final Exam - 8:00 a.m. (comprehensive) |
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